| Hb F-Xinjiang | Agamma25(B7)Gly->Arg; 75(E19)Ile->Thr |
|---|
| ELECTROPHORESIS | Hb FX moves between Hb S and Hb C at alkaline pH | ||
| IEF | Not reported | ||
| CHROMATOGRAPHY | Hb FX was isolated by DEAE-cellulose chromatography | ||
| CHAIN SEPARATION | Not reported | ||
| STRUCTURE STUDIES | Tryptic digestion of gammaX chain; separation of peptides by fin-gerprinting; amino acid analysis; sequencing | ||
| DNA ANALYSES | Not reported; presumed mutation GGA->CGA at codon 25 | ||
| NOTES | Found in a Chinese newborn of the Han nationality; Hb FX 7.7% of total Hb; the variant is somewhat unstable |
| REFERENCES | |||
| 1. | Hu, H. and Ma, M.; Hemoglobin, 11:465, 1987. | ||