Hb F-Xinjiang | Agamma25(B7)Gly->Arg; 75(E19)Ile->Thr |
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ELECTROPHORESIS | Hb FX moves between Hb S and Hb C at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX was isolated by DEAE-cellulose chromatography | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of gammaX chain; separation of peptides by fin-gerprinting; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation GGA->CGA at codon 25 | ||
NOTES | Found in a Chinese newborn of the Han nationality; Hb FX 7.7% of total Hb; the variant is somewhat unstable |
REFERENCES | |||
1. | Hu, H. and Ma, M.; Hemoglobin, 11:465, 1987. |