Hb F-Fukuyama	Agamma43(CD2)Asp->Asn; 75(E19)Ile->Thr

ELECTROPHORESIS		Not reported
IEF		Hb FX focuses slower than Hb F but faster than Hb A2
CHROMATOGRAPHY		Not reported
CHAIN SEPARATION		AgammaX = 33.1%; Ggamma = 45.8%; AgammaI = 21.1%
STRUCTURE STUDIES		Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation GAC->AAC at codon 43
NOTES		Found in a Japanese newborn; the authors consider the possibility of an additional gamma-thal to explain the high level of Hb FX (20.6% of total Hb)

REFERENCES
1.		Hidaka, K., Iuchi, I., Nakahara, H., and Iwakawa, G.: Hemoglobin, 13:93, 1989.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.