Hb Atlanta-Coventry | beta75(E19)Leu->Pro; |
---|---|
beta141(H19)Leu->0 |
NOTE: | This interesting variant was misidentified and corrected late by the same group of investigators; the leucine residue at position beta141 is not deleted but (partially) oxidized to hydroxyleucine; the same phenomenon has been observed for other Hb Atlanta heterozygotes |
REFERENCES | |||
1. | Brennan, S.O., Williamson, D., Symmans, W.A., and Carrell, R.W.: Hemoglobin, 10:225, 1986. | ||
2. | Brennan, S.O., Shaw, J., Allen, J., and George, P.M.: Br. J. Haematol., 81:99, 1992. | ||
3. | Brennan, S.O. Shaw, J.G., George, P.M., and Huisman, T.H.J.: Hemoglobin, 17:1, 1993. |