Hb F-Shanghai | Ggamma66(E10)Lys->Arg |
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ELECTROPHORESIS | No separation reported | ||
IEF | No separation reported | ||
CHROMATOGRAPHY | Not reported; no separation by DEAE-cellulose chromatography | ||
CHAIN SEPARATION | GgammaX = 35.5% of total gamma; Ggamma = 37.9%; Agamma = 26.6% | ||
STRUCTURE STUDIES | Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation AAG->AGG at codon 66 | ||
NOTES | Found in a Chinese newborn |
REFERENCES | |||
1. | Zeng, Y-T., Huang, S-Z., Nakatsuji, T., and Huisman, T.H.J.: Am. J. Hematol., 18: 235, 1985. |