Hb F-Saskatoon	Ggamma21(B3)Glu->Lys

ELECTROPHORESIS		Hb FX moves slower than Hb F at alkaline pH
IEF		Hb FX focuses between Hb A2 and Hb A2'
CHROMATOGRAPHY		Hb FX separates from Hb F and Hb A
CHAIN SEPARATION		Not reported
STRUCTURE STUDIES		Not done
DNA ANALYSES		A GAA->AAA mutation at codon 21
NOTES		Found in an American Indian baby; quantity in the heterozygote 16.2% of total Hb; 23.3% of total Hb F

REFERENCES
1.		Pobedimskaya, D.D., Molchanova, T.P., Huisman. T.H.J., Harding, S.R., and Bakanec, R.: Hemoglobin, 17:547, 1993.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.