Hb F-Poole	Ggamma130(H8)Trp->Gly

ELECTROPHORESIS		No separation observed at alkaline pH
IEF		Not reported
CHROMATOGRAPHY		Not reported
CHAIN SEPARATION		Not reported
STRUCTURE STUDIES		Tryptic digestion of Hb FX; separation of peptides by fingerprinting; amino acid analysis; sequencing
DNA ANALYSES		Not reported; presumed mutation TGG->GGG at codon 130
NOTES		Found in a Black-Caucasian baby living in Poole, Dorset, England; variant is unstable; baby had hemolytic anemia

REFERENCES
1.		Lee-Potter, J.P., Deacon-Smith, R.A., Simpkiss, M.J., Kamuzora, H., and Leh-mann, H.: J. Clin. Pathol., 28:317, 1975.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.