Hb F-Melbourne	Ggamma16(A13)Gly->Arg

ELECTROPHORESIS		Hb FX moves slower than Hb A and Hb F at alkaline pH
IEF		Not reported
CHROMATOGRAPHY		Hb FX was isolated by DEAE-cellulose chromatography
CHAIN SEPARATION		No information
STRUCTURE STUDIES		Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation GGC->CGC at codon 16
NOTES		Found in a Spanish baby living in Australia; quantity in the heterozygote: 26% of total Hb; 29% of total Hb F

REFERENCES
1.		Brennan, S.O., Smith, M.B., and Carrell, R.W.: Biochim. Biophys. Acta, 490:452, 1977.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.