Hb F-Granada | Ggamma22(B4)Asp->Val |
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ELECTROPHORESIS | Hb FX moves between Hb S and Hb C at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Not reported | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of AE-gammaX chain; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GAT->GTT at codon 22 | ||
NOTES | Found in a Spanish newborn; Hb FX 22% of total Hb |
REFERENCES | |||
1. | de Pablos, J.Ma. and Clegg, J.B.: Hemoglobin, 12:405, 1988. |