Hb F-Albaicin	Ggamma8(A5)Lys->Glu or Gln

ELECTROPHORESIS		Hb FX moves faster than Hb A at alkaline pH
IEF		No information
CHROMATOGRAPHY		No information
CHAIN SEPARATION		GgammaX = 29.2%; Ggamma = 50.6%; Agamma = 20.2%
STRUCTURE STUDIES		Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequence analysis was not possible
DNA ANALYSES		Not reported; presumed mutation AAG->CAG (Gln) or GAG (Glu) at codon 8
NOTES		Found in a Spanish newborn; quantity in the newborn ~29% of total gamma (reversed phase HPLC)

REFERENCES
1.		de Pablos, J.M., Wilson, J.B., Kutlar, A., Chen, S.S., and Huisman, T.H.J.: Hemoglobin, 10:655, 1986.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.