Hb A2-Zagreb	delta125(H3)Gln->Glu

CONTACT
ELECTROPHORESIS		Hb X moves between Hb A and Hb A2 at alkaline pH
IEF		Not reported
CHROMATOGRAPHY		Hb X elutes between Hb A2 and Hb A from a DEAE-cellulose column
STRUCTURE ANALYSIS		Tryptic digestion of AE-deltaX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSIS		Not reported; presumed mutation CAA->GAA at codon 125
NOTES		Found in a Yugoslavian (Croatian) family; occurred in association with a (deltabeta)o-thal

REFERENCES
1.		Juricic, D., Crepinko, I., Efremov, G.D., Lam, H. Webber, B.B., Headlee, M.G., and Huisman, T.H.J.: Hemoglobin, 7:443, 1983.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.