Hb A2-Yokoshima	delta25(B7)Gly->Asp

CONTACT		External
ELECTROPHORESIS		Not reported
IEF		Hb X focuses between Hb A and Hb A2
CHROMATOGRAPHY		Hb X was isolated by anion exchange HPLC
STRUCTURE ANALYSIS		Tryptic digestion of deltaX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSIS		Not reported; presumed mutation GGT->GAT at codon 25
NOTES		Found in a Japanese family; one member is a homozygote

REFERENCES
1.		Ohba, Y., Igarashi, M., Tsukahara, M., Nakashima, M., Sanada, C., Ami, M., Arai, Y., and Miyaji, T.: Hemoglobin, 9:613, 1985.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.