Hb A2-Wrens	delta98(FG5)Val->Met

CONTACT		Internal; heme to alpha2beta1 contacts
ELECTROPHORESIS		No separation observed
IEF		No separation observed
CHROMATOGRAPHY		No separation observed
STRUCTURE ANALYSIS		Not done
DNA ANALYSIS		A GTG->ATG mutation at codon 98
NOTES		Found in a Black family; variant is unstable and occurred in association with HPFH

REFERENCES
1.		Codrington, J.F., Kutlar, F., Harris, H.F., Wilson, J.B., Stoming, T.A., and Huisman, T.H.J.: Biochim. Biophys. Acta, 1009:87, 1989.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.