Hb A2-Puglia	delta26(B8)Glu->Asp

CONTACT		External; surface crevice
ELECTROPHORESIS		Hb X moves slightly slower than Hb A2 at alkaline pH
IEF		About the same
CHROMATOGRAPHY		Not reported
STRUCTURE ANALYSIS		Not reported
DNA ANALYSIS		A GAG->GAC mutation at codon 26
NOTES		Found in an Italian family in association with beta-thal (codon 39; C->T)

REFERENCES
1.		Loudianos, G., Porcu, S., Cossu, P., Tannoia, N., Vitucci, A., Campanale, D., Cao, A., and Pirastu, M.: Hum. Mut., 2:327, 1993.

---

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.