Hb A2-Melbourne	delta43(CD2)Glu->Lys

CONTACT		External
ELECTROPHORESIS		Hb X moves slower than Hb A2 at alkaline pH
IEF		Not reported
CHROMATOGRAPHY		Hb X was isolated by DEAE-Sephadex chromatography
STRUCTURE ANALYSIS		Tryptic digestion of deltaX chain; separation of peptides by cation exchange HPLC; amino acid analysis
DNA ANALYSIS		Not reported; presumed mutation GAG->AAG at codon 43
NOTES		Found in members of an Italian family living in Australia

REFERENCES
1.		Sharma, R.S., Harding, D.L., Wong, S.C., Wilson, J.B., Gravely, M.E., and Huisman, T.H.J.: Biochim. Biophys. Acta, 359:233, 1974.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.