Hb Zengcheng	beta114(G16)Leu->Met

CONTACT		Internal
HEMATOLOGY		Normal in the newborn
ELECTROPHORESIS		IEF detected a slightly faster moving beta chain variant
CHROMATOGRAPHY		The betaX and betaA chains can be separated by reversed phase HPLC
STRUCTURE STUDIES		The betaX chain was aminoethylated, digested with trypsin, and the resulting peptides separated by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSES		Not reported; presumed mutation CTG->ATG at codon 114
FUNCTION STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Discovered in a Chinese baby from Zengcheng, PR China; parents were not available for study
OTHER INFORMATION		None

REFERENCES
1.		Plaseska, D., Wilson, J.B., Gu, L-H., Kutlar, F., Huisman, T.H.J., Zeng, Y-T., and Shen, M.: Hemoglobin, 14:555, 1990.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.