Hb Sarrebourg	beta131(H9)Gln->Arg

CONTACT		Internal; alpha1beta1 contact
HEMATOLOGY		Iron-deficiency anemia in the carrier
ELECTROPHORESIS		Hb X and Hb A separate at alkaline pH; Hb X moves like Hb F, and between Hb F and Hb S on IEF
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Not reported in detail; only final data are presented
DNA ANALYSES		Not reported; presumed mutation CAG->CGG at codon 131
FUNCTION STUDIES		Normal
STABILITY		Unstable
OCCURRENCE		Found in a 9-year-old Turkish boy
OTHER INFORMATION		Hb X comprised ~30% of the total Hb

REFERENCES
1.		Duwig, I., North, M.L., Barth, J.G., Rieffel, M., Nierengarten, P., Arous, N., Riou, J., and Galacteros, F.: Abstract, Nouv. Rev. Fr. d'Hematol., 29:344, 1987.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.