Hb Quin-Hai	beta78(EF2)Leu->Arg

CONTACT		External
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X and Hb A separate at alkaline pH; Hb X moves between Hb F and Hb S
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis; sequencing
DNA ANALYSES		Not reported; presumed mutation CTG->CGG at codon 78
FUNCTION STUDIES		Not reported
STABILITY		Normal
OCCURRENCE		Found in a Chinese family
OTHER INFORMATION		Quantity in the heterozygote 21.7% (elution from cellulose acetate)

REFERENCES
1.		Jen, P.C., Chen, L.C., Chen, P.F., Wong, Y., Chen, L.F., Guo, Y.Y., Chang, F.Q., Chow, Y.C., and Chiu, Y.: Hemoglobin, 7:407, 1983.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.