Hb Nagasaki	beta17(A14)Lys->Glu

CONTACT		External
HEMATOLOGY		Not reported
ELECTROPHORESIS		Hb X moves faster than Hb A on starch gel at alkaline pH
CHROMATOGRAPHY		Hb X was isolated by CM-cellulose chromatography
STRUCTURE STUDIES		Tryptic digestion; fingerprinting; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation AAG->GAG at codon 17
FUNCTION STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Found in three members of a Japanese family living in Nagasaki, Japan
OTHER INFORMATION		Quantity in the heterozygote 30%; heterozygotes appear to be clinically normal

REFERENCES
1.		Maekawa, M., Maekawa, T., Fujiwara, N., Tabara, K., and Matsuda, G.: Int. J. Prot. Res., II:147, 1970.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.