Hb Machida | beta6(A3)Glu->Gln |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X moves with the mobility of Hb S by IEF | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; fingerprinting; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation GAG->CAG at codon 6 | ||
FUNCTION STUDIES | Normal | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a Japanese family | ||
OTHER INFORMATION | Quantity in the heterozygote 40-43% |
REFERENCES | |||
1. | Harano, T., Harano, K., Ueda, S., Shibata, S., Imai, K., and Seki, M.: Hemoglobin, 6:531, 1982. |