Hb Kenitra	beta69(E13)Gly->Arg

CONTACT		External
HEMATOLOGY		Probably normal; the proband had an additional alpha-thal, resulting in microcytosis, hypochromia
ELECTROPHORESIS		Hb X slowly separates from Hb A at alkaline pH
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Tryptic digestion of AE-betaX chain; separation of peptides by reversed phase HPLC; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation GGT->CGT at codon 69
FUNCTION STUDIES		Not determined
STABILITY		Normal
OCCURRENCE		Found in a Moroccan family
OTHER INFORMATION		Quantity in the heterozygote ~55% (densitometry)

REFERENCES
1.		Delanoe-Garin, J., Arous, N., Blouquit, Y., Hafsia, R., Bardakdjian, J., Lacombe, C., Rosa, J., and Galacteros, F.: Hemoglobin, 9:1, 1985.

---

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.