Hb G-Taiwan-Ami | beta25(B7)Gly->Arg |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X and Hb A separate well at alkaline pH; Hb X takes the position of Hb G or Hb S | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; fingerprinting; amino acid analysis; C-terminal analysis by carboxypeptidase A and B; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation GGT->CGT at codon 25 | ||
FUNCTION STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in several Aborigines of the Ami tribe in Taiwan | ||
OTHER INFORMATION | None |
REFERENCES | |||
1. | Blackwell, R.Q. and Liu, C-S.: Biochem. Biophys. Res. Commun., 30:690, 1968. |