Hb Christchurch	beta71(E15)Phe->Ser

CONTACT		Heme contact
HEMATOLOGY		Heinz body hemolytic anemia in the heterozygote
ELECTROPHORESIS		Hb X moves with Hb A on various media at various pH values
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		14C-labeled hydrolysate; fingerprinting; chymotrypsin; amino acid analysis; autoradiographs
DNA ANALYSES		Not reported; presumed mutation TTT->TCT at codon 71
FUNCTION STUDIES		Not reported
STABILITY		Unstable
OCCURRENCE		Found in an 18-year-old female living in Australia
OTHER INFORMATION		Quantity in the heterozygote about 22%

REFERENCES
1.		Carrell, R.W. and Owen, M.C.: Biochim. Biophys. Acta, 236:507, 1971.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.