Hb Alamo	beta19(B1)Asn->Asp

CONTACT		External
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X moves faster than Hb A on starch gel at alkaline pH, and to the position of Hb A on citrate agar at acidic pH
CHROMATOGRAPHY		Hb X and Hb A were separated by DEAE-cellulose chromatography
STRUCTURE STUDIES		Tryptic digestion; cation exchange chromatography; amino acid analysis; sequencing
DNA ANALYSES		Not reported; presumed mutation AAC->GAC at codon 19
FUNCTION STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Found in a Black family
OTHER INFORMATION		Quantity in the heterozygote 52-54% (some Hb A1 is probably included)

REFERENCES
1.		Lam, H., Wilson, J.B., Harris, H., Gravely, M., and Huisman, T.H.J.: Hemoglobin, 1:703, 1977.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.