Hb Ramona	alpha24(B5)Tyr->Cys

CONTACT		Internal
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X was detected by IEF; it moves slightly faster than Hb A
CHROMATOGRAPHY		No separation by cation or anion exchange chromatography
STRUCTURE STUDIES		No separation from Hb A by cation exchange HPLC; no protein analysis reported
DNA ANALYSES		Mutation in the alpha1 gene: TAT->TGT at codon 24
FUNCTIONAL STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Found in a female of Spanish descent
OTHER INFORMATION		Quantity in the heterozygote could not be determined

REFERENCES
1.		Pobedimskaya, D.D., Molchanova, T.P., and Huisman, T.H.J.: Hemoglobin, 18: 365, 1994.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.