Hb Ramona | alpha24(B5)Tyr->Cys |
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CONTACT | Internal | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X was detected by IEF; it moves slightly faster than Hb A | ||
CHROMATOGRAPHY | No separation by cation or anion exchange chromatography | ||
STRUCTURE STUDIES | No separation from Hb A by cation exchange HPLC; no protein analysis reported | ||
DNA ANALYSES | Mutation in the alpha1 gene: TAT->TGT at codon 24 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a female of Spanish descent | ||
OTHER INFORMATION | Quantity in the heterozygote could not be determined |
REFERENCES | |||
1. | Pobedimskaya, D.D., Molchanova, T.P., and Huisman, T.H.J.: Hemoglobin, 18: 365, 1994. |