Hb J-Medellin | alpha22(B3)Gly->Asp |
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CONTACT | External | ||
HEMATOLOGY | Not reported | ||
ELECTROPHORESIS | Hb X moves faster than Hb J at alkaline pH | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GGC->GAC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in two families from Colombia | ||
OTHER INFORMATION | Quantity in heterozygotes 20% |
REFERENCES | |||
1. | Gottlieb, A.J., Restrepo, A., and Itano, H.A., Fed. Proc., 23:172, 1964. |