Hb J-Abidjan | alpha51(CE9)Gly->Asp |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | This fast-moving variant separates from Hb A at alkaline pH; moves to the position of Hb J on paper and cellulose acetate | ||
CHROMATOGRAPHY | Hb X was isolated on a DEAE-Sephadex column | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GGC->GAC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a Yacouba male living at the Ivory Coast | ||
OTHER INFORMATION | Quantity in heterozygotes about 23% |
REFERENCES | |||
1. | Cabannes, R., Renaud, R., Mauran, A., Pennors, H., Charlesworth, D., Price, B.G., and Lehmann, H.: Nouv. Rev. Fr. d'Hematol., 12:289, 1972. |