Hb G-Audhali | alpha23(B4)Glu->Val |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X moves to the position of Hb G at alkaline pH | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GAG->GTG; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in two Black families living in Southern Arabia | ||
OTHER INFORMATION | Quantity in heterozygotes ~25% |
REFERENCES | |||
1. | Marengo-Rowe, A.J., Beale, D., and Lehmann, H.: Nature, 219:1164, 1968. |