Hb Cemenelum	alpha92(FG4)Arg->Trp

CONTACT		alpha1beta2 contact
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X separates from Hb A by preparative flat-bed IEF
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; ion spray mass spectrometry
DNA ANALYSES		Not reported; presumed mutation CGG->TGG; alpha2 or alpha1
FUNCTIONAL STUDIES		Increased oxygen affinity
STABILITY		Not reported
OCCURRENCE		Found in a French Caucasian woman
OTHER INFORMATION		None

REFERENCES
1.		Kister, J., Soummer, A.M., M'Rad, A., Bohn, B., Promé, Cappellino, B., Chambon, P., Wajcman, H., and Galacteros, F.: Abstract, Journees Scientifique du Club de L'Hemoglobine, Strasbourg, France, June, 1993.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.