Hb Cemenelum | alpha92(FG4)Arg->Trp |
---|
CONTACT | alpha1beta2 contact | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X separates from Hb A by preparative flat-bed IEF | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; ion spray mass spectrometry | ||
DNA ANALYSES | Not reported; presumed mutation CGG->TGG; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Increased oxygen affinity | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a French Caucasian woman | ||
OTHER INFORMATION | None |
REFERENCES | |||
1. | Kister, J., Soummer, A.M., M'Rad, A., Bohn, B., Promé, Cappellino, B., Chambon, P., Wajcman, H., and Galacteros, F.: Abstract, Journees Scientifique du Club de L'Hemoglobine, Strasbourg, France, June, 1993. |