Hb Albany-Suma | alpha11(A9)Lys->Asn |
---|
CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X moves to the position of Hb J on starch gel (pH 9.0) and cellulose acetate (pH 8.9); it moves with Hb A on citrate agar (pH 6.0) | ||
CHROMATOGRAPHY | Hb X was isolated on a DEAE-cellulose column | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation AAG->AAC or AAT; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a 15-year-old Black female | ||
OTHER INFORMATION | Quantity in the heterozygote 23.8% |
REFERENCES | |||
1. | Webber, B.B., Lam, H., Wilson, J.B., and Huisman, T.H.J.: Hemoglobin, 7:257, 1983. | ||
2. | Shimasaki, S., Iuchi, I., Hidaka, K., and Mizuta, W.: Jpn. J. Hum. Genet., 28:127, 1983. |