Hb Al-Ain Abu Dhabi | alpha18(A16)Gly->Asp |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X moves faster than Hb A at alkaline pH | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GGC->GAC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Normal | ||
STABILITY | Normal | ||
OCCURRENCE | Found in a family living in the United Arab Emirates | ||
OTHER INFORMATION | Quantity in heterozygotes 25-31.6% |
REFERENCES | |||
1. | Abbes, S., M'Rad, A., Fitzgerald, P.A., Dormer, P., Blouquit, Y., Kister, J., Galacteros, F., and Wajcman, H.: Hemoglobin, 16:355, 1992. |