Hb F-Kuala Lumpur | Agamma22(B4)Asp->Gly |
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ELECTROPHORESIS | Hb FX moves between Hb S and Hb C at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX and Hb A cannot be separated by DEAE-Sephadex chromatography | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of AE-gammaX chain; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GAT->GGT at codon 22 | ||
NOTES | Found in a Few Indian newborn babies; Hb FX 11% of total Hb |
REFERENCES | |||
1. | Lie-Injo, L.E., Wiltshire, B.G., and Lehmann, H.: Biochim. Biophys. Acta, 322:224, 1973. |