TABLE V.   Beta-Thalassemia Alleles in Turks and Turkish Cypriots (number of chromosomes) (references in parentheses)

Turks Turkish Cypriots
Allele Patients & Relatives
(1) 		Patients & Relatives
(2) 		Patients & Relatives
(3)
(4) 		Adana Region
(5) 		Total %
(5)
(6) 		Total %
-101, C->T 5     1   6 0.48        
-87, C->G 2 2 2 6   12 0.98        
-30, T->A 16     17   33 2.69        
-28, A->C 2     1   3 0.24        
Codon 5, -CT 6     16   22 1.79        
Codon 6, -A 1 2   2   5 0.40        
Codon 8, -AA 35 5 13 21 7 81 6.60        
Codons 8/9, +G 5 1   13   19 1.55        
Codon 15, TGG->TAG   2       2 0.16        
Codon 27, C->T       1   1 0.08        
IVS-I-1, G->A 13 3 4 19 15 54 4.40 17 23 40 9.35
IVS-I-5, G->A 1         1 0.08        
IVS-I-5, G->C 7     5   12 0.97        
IVS-I-5, G->T 4   2     6 0.48        
IVS-I-6, T->C 94 5 22 43 17 181 14.75 18 17 35 8.18
IVS-I-110, G->A 207 21 40 181 70 519 42.29 172 137 309 72.19
IVS-I-116, T->G       1   1 0.08        
IVS-I-130, G->A 2         2 0.16        
Codon 39, C->T 24 2 2 16 4 48 3.91 2 3 5 1.17
IVS-II-1, G->A 61 1 8 15 6 91 7.41        
IVS-II-745, C->G 15 5 1 10 11 42 3.42 15 11 26 6.07
Unknown; others 18 3 0 61 4 86 7.00 8 5 13 3.03
TOTAL 518 52 94 429 134 1227   232 196 428  

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This material is from the book A Syllabus of Thalassemia Mutations (1997) by Titus H.J. Huisman, Marianne F.H. Carver, and Erol Baysal, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1997 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without permission in writing from the Author.