Hb Zambia	alpha60(E9)Lys->Asn

CONTACT		External
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Only studied by paper electrophoresis; it moves faster than Hb A at alkaline pH
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation AAG->AAC or AAT; alpha2 or alpha1
FUNCTIONAL STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Found in four unrelated families in Zambia
OTHER INFORMATION		None

REFERENCES
1.		Barclay, G.P.T., Charlesworth, D., and Lehmann, H.: Br. Med. J., 4:595, 1969.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.