Hb GuiZhou | alpha77(EF6)Pro->Arg |
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CONTACT | External | ||
HEMATOLOGY | Normal in the heterozygote | ||
ELECTROPHORESIS | Hb X has a mobility like Hb G on cellulose acetate at alkaline pH | ||
CHROMATOGRAPHY | Not reported | ||
STRUCTURE STUDIES | Separation of tryptic peptides by reversed phase HPLC; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation CCC->CGC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Not reported | ||
STABILITY | Normal | ||
OCCURRENCE | Found in a 47-year-old Chinese woman of the Miao ethnic group and four members of her family | ||
OTHER INFORMATION | Quantity in the heterozygote ~25% |
REFERENCES | |||
1. | Chih-chuan, L., Fei, X., Kegong, Y., Songsen, C., Peichen, J., Maoqi, Z., and Zhiheng, Z.: Hemoglobin, 8:387, 1984. |