Hb F-Iwata | Agamma72(E16)Gly->Arg |
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ELECTROPHORESIS | Hb FX moves slightly slower than Hb S at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX elutes between Hb A2 and Hb A from a DEAE-cellulose column | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of gammaX chain; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GGA->CGA at codon 72 | ||
NOTES | Found in a few Japanese newborn babies; quantity in the heterozygote ~11% of total Hb F |
REFERENCES | |||
1. | Fuyuno, K., Torigoe, T., Ohba, Y., Matsuoka, M., and Miyaji, T.: Hemoglobin, 5: 139, 1981. |