Course Materials for Bioinformatics I
What is Bioinformatics I?
Nucleic Acids Research 2002 Database Issue
Study guide for exam:
part 1 and
Notes on the genome paper in Nature.
Notes about PipMaker.
Notes about extensions to PipMaker.
Paper on UCSC Genome Browser.
The Browser itself.
Users guide to the human genome.
Published in Nature Genetics, September 2002.
Alignment scores and PSI-Blast
notes on dynamic programming
outline of the Blast program
paper on Gapped Blast and PSI Blast
amino acid substitution scores
probabilistic sequence models
probabilistic sequence models, part 2
simple example of Viterbi decoding
paper on GenScan
Some of the materials will be presented as PostScript and PDF documents,
so you will need to handle at least one of these formats.
If your system doesn't already have one, you may want to fetch and install a
free PostScript/PDF viewer manufactured by Aladdin Inc, called
The Aladdin web page has instructions for attaching it to
Netscape or MS Internet-Explorer.
Another popular program for reading PDF files is
Adobe Acrobat Reader.
You might find it amusing to learn
how I got involved in bioinformatics.