Hb F-Tokyo Ggamma34(B16)Val->Ile
         
ELECTROPHORESIS No separation observed
IEF Not reported
CHROMATOGRAPHY Not reported
CHAIN SEPARATION GgammaX = 31.3%; Ggamma = 34.4%; Agamma = 34.4%
STRUCTURE STUDIES Isolation of GgammaX by preparative reversed phase HPLC; tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing
DNA ANALYSES Not reported; presumed mutation GTC->ATC at codon 34
NOTES Found in a Japanese newborn
       
REFERENCES
1. Chen, S.S., Wilson, J.B., Webber, B.B., Huisman, T.H.J., Miwa, S., and Amenomori, Y.: Hemoglobin, 9:25, 1985.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.