Hb Zengcheng | beta114(G16)Leu->Met |
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CONTACT | Internal | ||
HEMATOLOGY | Normal in the newborn | ||
ELECTROPHORESIS | IEF detected a slightly faster moving beta chain variant | ||
CHROMATOGRAPHY | The betaX and betaA chains can be separated by reversed phase HPLC | ||
STRUCTURE STUDIES | The betaX chain was aminoethylated, digested with trypsin, and the resulting peptides separated by reversed phase HPLC; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation CTG->ATG at codon 114 | ||
FUNCTION STUDIES | Not reported | ||
STABILITY | Not reported | ||
OCCURRENCE | Discovered in a Chinese baby from Zengcheng, PR China; parents were not available for study | ||
OTHER INFORMATION | None |
REFERENCES | |||
1. | Plaseska, D., Wilson, J.B., Gu, L-H., Kutlar, F., Huisman, T.H.J., Zeng, Y-T., and Shen, M.: Hemoglobin, 14:555, 1990. |