Hb G-Taiwan-Ami beta25(B7)Gly->Arg
         
CONTACT External
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X and Hb A separate well at alkaline pH; Hb X takes the position of Hb G or Hb S
CHROMATOGRAPHY Not reported
STRUCTURE STUDIES Tryptic digestion; fingerprinting; amino acid analysis; C-terminal analysis by carboxypeptidase A and B; sequencing
DNA ANALYSES Not reported; presumed mutation GGT->CGT at codon 25
FUNCTION STUDIES Not reported
STABILITY Not reported
OCCURRENCE Found in several Aborigines of the Ami tribe in Taiwan
OTHER INFORMATION None
       
REFERENCES
1. Blackwell, R.Q. and Liu, C-S.: Biochem. Biophys. Res. Commun., 30:690, 1968.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.