Hb Shenyang alpha26(B7)Ala->Glu
         
CONTACT Internal
HEMATOLOGY Anemia in the heterozygote; some target cells
ELECTROPHORESIS Hb X moves like Hb J on cellulose acetate and starch gel at alkaline pH
CHROMATOGRAPHY Not reported
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis; sequencing analysis
DNA ANALYSES Not reported; presumed mutation GCG->GAG; alpha2 or alpha1
FUNCTIONAL STUDIES Not reported
STABILITY Slightly unstable
OCCURRENCE Found in a 23-year-old Chinese male
OTHER INFORMATION Quantity in the heterozygote 21.5%
       
REFERENCES
1. Zeng, Y-T., Huang, S-Z., Zhou, X-D., Qiu, X-K., Dong, Q-Y., Li, M-Y., and Bai, J-H.: Hemoglobin, 6:625, 1982.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.