Hb Ramona alpha24(B5)Tyr->Cys
CONTACT Internal
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X was detected by IEF; it moves slightly faster than Hb A
CHROMATOGRAPHY No separation by cation or anion exchange chromatography
STRUCTURE STUDIES No separation from Hb A by cation exchange HPLC; no protein analysis reported
DNA ANALYSES Mutation in the alpha1 gene: TAT->TGT at codon 24
STABILITY Not reported
OCCURRENCE Found in a female of Spanish descent
OTHER INFORMATION Quantity in the heterozygote could not be determined
1. Pobedimskaya, D.D., Molchanova, T.P., and Huisman, T.H.J.: Hemoglobin, 18: 365, 1994.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.