Hb Port Phillip alpha91(FG3)Leu->Pro
CONTACT Heme and alpha1beta2 contacts
HEMATOLOGY Mild anemia; reticulocytosis in the heterozygote
ELECTROPHORESIS Hb X moves to the position of Hb F on starch gel at alkaline pH
CHROMATOGRAPHY Hb X and Hb A separate incompletely on a DEAE-Sephadex column
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES Not reported; presumed mutation CTT->CCT; alpha2 or alpha1T
OCCURRENCE Found in a Chinese female
OTHER INFORMATION Quantity in the heterozygote about 7%
1. Brennan, S.O., Tauro, G.P., Melrose, W., and Carrell, R.W.: FEBS Lett., 81:115, 1977.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.