Hb Lisbon alpha23(B4)Glu->Asp
CONTACT External
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS The best separation of Hb X and Hb A is by IEF; the electrophoretic pattern showed a slight decrease in pI
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting on an HPLC column; amino acid analysis
DNA ANALYSES Not reported; presumed mutation GAG->GAT; alpha2 or alpha1
STABILITY Not reported
OCCURRENCE Found in a 31-year-old Portuguese male
OTHER INFORMATION Quantity in the heterozygote not reported
1. Wajcman, H., Bost, M., Blouquit, Y., Préhu, C., Riou, J., and Galacteros, F.: Hemoglobin, 18:427, 1994.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.