Hb Cemenelum alpha92(FG4)Arg->Trp
CONTACT alpha1beta2 contact
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X separates from Hb A by preparative flat-bed IEF
STRUCTURE STUDIES Tryptic digestion; separation of peptides by reversed phase HPLC; amino acid analysis; ion spray mass spectrometry
DNA ANALYSES Not reported; presumed mutation CGG->TGG; alpha2 or alpha1
FUNCTIONAL STUDIES Increased oxygen affinity
STABILITY Not reported
OCCURRENCE Found in a French Caucasian woman
1. Kister, J., Soummer, A.M., M'Rad, A., Bohn, B., Promé, Cappellino, B., Chambon, P., Wajcman, H., and Galacteros, F.: Abstract, Journees Scientifique du Club de L'Hemoglobine, Strasbourg, France, June, 1993.

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.