Hb Beijing alpha16(A14)Lys->Asn
         
CONTACT External
HEMATOLOGY Normal in the heterozygote
ELECTROPHORESIS Hb X moves ahead of Hb A at alkaline pH; it moves between Hb A and Hb H, probably at position of Hb J on cellulose acetate (pH 8.6)
CHROMATOGRAPHY Not reported
STRUCTURE STUDIES Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis; sequencing of selected peptides
DNA ANALYSES Not reported; presumed mutation AAG->AAC or AAT; alpha2 or alpha1
FUNCTIONAL STUDIES Not reported
STABILITY Normal
OCCURRENCE Found in a Chinese family
OTHER INFORMATION Quantity in heterozygotes 19.3%
       
REFERENCES
1. Liang, C.C., Chen, S., Yang, K., Jia, P., Ma, Y., Li, T., Ni, X., Wang, X., Deng, Q., and Yao, S.: Hemoglobin, 6:629, 1982.


This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.