Hb Atago | alpha85(F6)Asp->Tyr |
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CONTACT | External | ||
HEMATOLOGY | Not reported | ||
ELECTROPHORESIS | Hb X moves slower than Hb F on starch gel at alkaline pH | ||
CHROMATOGRAPHY | The variant was isolated on a CM-cellulose column | ||
STRUCTURE STUDIES | Tryptic digestion; separation of peptides by fingerprinting; amino acid analysis | ||
DNA ANALYSES | Not reported; presumed mutation GAC->TAC; alpha2 or alpha1 | ||
FUNCTIONAL STUDIES | Increased oxygen affinity | ||
STABILITY | Not reported | ||
OCCURRENCE | Found in a Japanese female | ||
OTHER INFORMATION | Quantity in the heterozygote 22-24% |
REFERENCES | |||
1. | Fujiwara, N., Maekawa, T., and Matsuda, G.: Int. J. Prot. Res., 3:35, 1971. |