Hb F-Kotobuku | Agamma6(A3)Glu->Gly |
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ALSO KNOWN AS | Izumi | ||
ELECTROPHORESIS | Hb FX moves slightly slower than Hb S at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX elutes between Hb A2 and Hb A on a DEAE-cellulose column | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of AE-gammaX chain; separation of peptides by fingerprinting; amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation GAG->GGG at codon 6 | ||
NOTES | Found in a Japanese baby; quantity in the heterozygote not reported |
REFERENCES | |||
1. | Yoshinaka, H., Ohba, Y., Hattori, Y., Matsuoka, M., Miyaji, T., and Fuyuno, K.: Hemoglobin, 6:37, 1982. | ||
2. | Wada, Y., Hayashi, A., Masanori, I., Katakuse, T., Ichihara, H., Nakabushi, T., Matsuo, T., Sakurai, T., and Matsuda, H.: Biochim. Biophys. Acta, 749:244, 1983. |