Hb F-Cobb | Agamma37(C3)Trp->Gly |
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ELECTROPHORESIS | Hb FX moves slower than Hb F at alkaline pH | ||
IEF | Not reported | ||
CHROMATOGRAPHY | Hb FX can be separated from Hb A and Hb F by DEAE-cellulose chromatography | ||
CHAIN SEPARATION | Not reported | ||
STRUCTURE STUDIES | Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC amino acid analysis; sequencing | ||
DNA ANALYSES | Not reported; presumed mutation TGG->GGG at codon 37 | ||
NOTES | Found in a Caucasian baby; no quantitative data at birth |
REFERENCES | |||
1. | Chen, S.S., Webber, B.B., Kutlar, A., Wilson, J.B., and Huisman, T.H.J.: 9:617, 1985. |