High Information Content Regions Locating Utility

Regions of high information content will be determined in the multiple alignment as the corresponding positions in the "human" sequence.   More information

The alignment to be used is: .

This alignment will be examined from: to: in "human",
and these offsets are relative to: The beginning of the human sequence file
The beginning of GenBank's HUMHBB locus.
(NOTES:   If you have chosen to use the "Old beta-globin alignment", then these two origins are the same, while the "New beta-globin alignment" begins 2687 bp 5' to HUMHBB. The output is always labeled relative to the beginning of the sequence files used in the alignment.)

Information content for alignment columns will be adjusted by subtracting:

Furthermore, constant value will be subtracted from the calculated information content of any column (this is in addition to subtracting the average, if any).

Minimal length of a region of high information content necessary for it to be recognized is: .

Minimal number of sequences which must be active (already started and not yet ended) within a region of high information content must be: .

Please choose the method of gap treatment:

The results of this tool should be presented as:

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Press to determine the regions, or to restore defaults.