Hb A2-Yokoshima | delta25(B7)Gly->Asp |
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CONTACT | External | ||
ELECTROPHORESIS | Not reported | ||
IEF | Hb X focuses between Hb A and Hb A2 | ||
CHROMATOGRAPHY | Hb X was isolated by anion exchange HPLC | ||
STRUCTURE ANALYSIS | Tryptic digestion of deltaX chain; separation of peptides by reversed phase HPLC; amino acid analysis; sequencing | ||
DNA ANALYSIS | Not reported; presumed mutation GGT->GAT at codon 25 | ||
NOTES | Found in a Japanese family; one member is a homozygote |
REFERENCES | |||
1. | Ohba, Y., Igarashi, M., Tsukahara, M., Nakashima, M., Sanada, C., Ami, M., Arai, Y., and Miyaji, T.: Hemoglobin, 9:613, 1985. |